Team News
 Lyon
Alexandre Lacazette was rested in Lyon's 3-1 defeat to Bordeaux at the weekend but will start here.
Sergi Darder could push for a start here.
 Valencia
Valencia will still be without goalkeepers Mat Ryan and Diego Alves, and they've been joined on the sidelines by full-back Jose Gaya in recent weeks.
Lucas Orban is expected to continue in Gaya's absence, with Aymen Abdennour likely to return having missed out from the weekend's action.
Prediction
Both sides are looking for their first win of the group stage. Lyon were held to a shock 1-1 draw away to the 9-men of Gent, whereas Valencia were beaten 3-2 at home to group leaders Zenit St. Petersburg.
Valencia have a decent record away to French teams, having won four and drawn five of their 11 previous encounters. However, they have already tasted defeat on French soil this season, with a 2-1 defeat to Monaco in their Champions League qualifer last month.
Lyon have really dipped since Nabil Fekir's injury and they might come up short again on this occasion. Valencia themselves have struggled for consistency this season, having won just two of their opening six league games.

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